Detection of regional DNA methylation using DNA-graphene affinity interactions
نویسندگان
چکیده
منابع مشابه
Detection of regional DNA methylation using DNA-graphene affinity interactions.
We report a new method for the detection of regional DNA methylation using base-dependent affinity interaction (i.e., adsorption) of DNA with graphene. Due to the strongest adsorption affinity of guanine bases towards graphene, bisulfite-treated guanine-enriched methylated DNA leads to a larger amount of the adsorbed DNA on the graphene-modified electrodes in comparison to the adenine-enriched ...
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ژورنال
عنوان ژورنال: Biosensors and Bioelectronics
سال: 2017
ISSN: 0956-5663
DOI: 10.1016/j.bios.2016.09.016